By Fumio Hanaoka,Kaoru Sugasawa
This e-book is a entire evaluate of the exact molecular mechanisms of and sensible crosstalk one of the replication, recombination, and service of DNA (collectively referred to as the "3Rs") and the similar tactics, with detailed recognition in their organic and medical outcomes. The 3Rs are primary molecular mechanisms for organisms to take care of and occasionally deliberately modify genetic info. DNA replication, recombination, and service, separately, were vital topics of molecular biology considering the fact that its emergence, yet we now have lately turn into acutely aware that the 3Rs are literally even more in detail on the topic of each other than we used to gain. additionally, the 3R learn fields were turning out to be much more interdisciplinary, with larger realizing of molecular mechanisms underlying different very important methods, resembling chromosome buildings and services, cellphone cycle and checkpoints, transcriptional and epigenetic rules, and so forth. This publication includes 7 components and 21 chapters: half 1 (Chapters 1–3), DNA Replication; half 2 (Chapters 4–6), DNA Recombination; half three (Chapters 7–9), DNA fix; half four (Chapters 10–13), Genome Instability and Mutagenesis; half five (Chapters 14–15), Chromosome Dynamics and services; half 6 (Chapters 16–18), mobile Cycle and Checkpoints; half 7 (Chapters 19–21), interaction with Transcription and Epigenetic legislation. This quantity should still allure the nice curiosity of graduate scholars, postdoctoral fellows, and senior scientists in wide study fields of simple molecular biology, not just the center 3Rs, but additionally a few of the similar fields (chromosome, mobilephone cycle, transcription, epigenetics, and related areas). also, researchers in neurological sciences, developmental biology, immunology, evolutionary biology, and plenty of different fields will locate this booklet valuable.
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Extra resources for DNA Replication, Recombination, and Repair: Molecular Mechanisms and Pathology
DNA Replication, Recombination, and Repair: Molecular Mechanisms and Pathology by Fumio Hanaoka,Kaoru Sugasawa