Nucleoside Triphosphates and their Analogs: Chemistry, - download pdf or read online

By Morteza Vaghefi

ISBN-10: 1574444980

ISBN-13: 9781574444988

Used generally in mobile and molecular biology study and cytogenetic functions, nucleotide analogs are at present on hand for the therapy of varied ailments. Nucleoside Triphosphate and Their Analogs: Chemistry, Biotechnology, and organic functions good points the contributions of 18 scientists from either academia and within the first entire resource committed totally to nucleoside triphosphate (NTP). The textual content offers collective info at the chemical, physiochemical, and organic homes of either average and transformed NTP along their software in lifestyles sciences.

This ebook examines the structural parts of NTPs' varied organic homes and healing results, together with cytotoxic compounds, antiviral brokers, and immunosuppressive molecules. The textual content describes artificial equipment used for every type of nucleotides and stories households of enzymes that rely on nucleotides for assembling DNA and RNA molecules. This e-book additionally emphasizes the major position NTP performs within the worldwide monitoring of conformational alterations in nucleic acids and nucleic acid complexes and the research of mobile methods and genetic fabric. the writer info the pharmaceutical and diagnostic functions of NTP amendment and the way fluorescent classified nucleotide analogs supply delicate probes for learning the constitution, dynamics, and interactions of nucleic acids.

Nucleoside Triphosphate and Their Analogs: Chemistry, Biotechnology, and organic purposes discusses the possibility of present purposes and destiny examine into context with an in-depth research of the position anticancer and antiviral nucleoside analogs play in clinical remedies, together with antiretroviral treatment regimens (for the remedy of HIV), anti-rejection remedy for organ transplants, hematological malignancy remedy, and the therapy of nonmalignant problems, reliable tumors, immunologic illnesses, and a number of sclerosis.

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Nucleoside Triphosphates and their Analogs: Chemistry, Biotechnology, and Biological Applications by Morteza Vaghefi

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