Regulation of Gene Expression by Small RNAs - download pdf or read online

By Rajesh K. Gaur,John J. Rossi

ISBN-10: 0849391695

ISBN-13: 9780849391699

ISBN-10: 1138111732

ISBN-13: 9781138111738

New Findings Revolutionize techniques of Gene Function

Endogenous small RNAs were present in numerous organisms, together with people, mice, flies, worms, fungi, and micro organism. moreover, it’s been proven that microRNAs performing as mobile rheostats be ready to modulate gene expression. In larger eukaryotes, microRNAs could keep watch over up to 50 percentage of gene expression.

Regulation of Gene Expression through Small RNAs brings jointly the pioneering paintings of researchers who talk about their paintings concerning a large choice of small RNA regulatory pathways in organisms starting from micro organism to people. as well as exploring the biogenesis and processing of those regulatory RNAs, additionally they examine the practical value of those pathways in host organisms. aiding present and destiny researchers, this precise groundbreaking paintings —

  • Provides a collection of state-of-the-art assets for the examine of microRNA ontology and function

  • Includes a expertise consultant for these looking to assay microRNA expression

  • Explores the mechanisms through which microRNAs control gene expression in animal cells, together with the law of gene expression by way of RNA-mediated transcriptional gene silencing

  • Discusses a quick and inexpensive process for reversing genetic impacts in mammals

  • Looks at breakthroughs within the use of microRNA-based remedy for HIV and melanoma

This quantity captures the essence of the breadth and pleasure surrounding the newly came upon regulatory roles of small RNAs. The robust new process within the research of gene functionality defined during this textual content is resulting in a few awesome findings that experience the capability to revolutionize our knowing of genetic functionality and the remedy of illnesses differently thought of intractable.

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Regulation of Gene Expression by Small RNAs by Rajesh K. Gaur,John J. Rossi

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