By Pierfausto Seneci
The final decade has obvious a quick enlargement in combinatorial applied sciences, a box the place chemistry disciplines intersect with automation, facts, and knowledge technological know-how, in addition to yes organic disciplines. Reflecting those multidisciplinary tendencies, this new paintings offers a accomplished review of an important points of solid-phase synthesis (SPS), combinatorial chemistry, and comparable combinatorial applied sciences. It essentially demonstrates how SPS and combinatorial chemistry have prolonged their software from the pharmaceutical enviornment to new parts, together with biotechnology, fabric sciences, catalysis, and agrochemical industries, and explores intimately concepts for making plans, designing, getting ready, and checking out of combinatorial libraries in quite a few disciplines. Designed to satisfy the desires of either skilled combinatorial chemists and novices to the sector, Solid-Phase Synthesis and Combinatorial Technologies:
- Surveys the newest advancements in SPS and combinatorial chemistry
- Explains the total technique, from identifying the necessity for a library to the main points worthy for synthesis of the library
- Discusses selection of structure, dimension, and the explanation at the back of the layout of every artificial step
- Surveys the analytical innovations and the purification tools used to signify and purify combinatorial libraries
- Employs a lot of examples to demonstrate very important concepts
- Includes difficulties aimed at employing received wisdom and designing the stairs to SPS/library synthesis
- Describes the standard regulate and task screening of combinatorial libraries for varied applications
- Features an in depth bibliography of greater than 1,700 proper sources
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Solid-Phase Synthesis and Combinatorial Technologies (Wiley-Interscience) by Pierfausto Seneci