By K. Lenhard Rudolph
Telomere shortening represents one of many easy points of aging and telomere disorder may give a contribution to the buildup of DNA harm in the course of growing older. This booklet summarizes proof and knowledge indicating that telomere disorder affects human growing older, ailments and melanoma. The booklet describes our present wisdom on checkpoints that restrict mobile lifespan and survival according to telomere disorder. there's particular specialize in grownup stem cells.
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Telomeres and Telomerase in Aging, Disease, and Cancer: Molecular Mechanisms of Adult Stem Cell Ageing by K. Lenhard Rudolph