Shinsuke Inuki's Total Synthesis of Bioactive Natural Products by PDF

By Shinsuke Inuki

ISBN-10: 4431540423

ISBN-13: 9784431540427

ISBN-10: 4431561102

ISBN-13: 9784431561101

the writer has built novel methodologies for hugely effective development of functionalized heterocycles by way of palladium-catalyzed domino/cascade cyclization of allenes and comparable compounds containing acceptable nucleophilic group(s). in keeping with those methodologies, enantioselective overall syntheses of bioactive normal items, pachastrissamine (26% total yield in seven steps), lysergic acid (4.0% total yield in fifteen steps), lysergol (3.6% total yield in fifteen steps) and isolysergol (8.2% total yield in 11 steps) were accomplished. those are extra facile man made path than these formerly pronounced. those findings may give a contribution to the advance of effective man made equipment for biologically lively compounds containing a posh structure.

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Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds (Springer Theses) by Shinsuke Inuki


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